Lil Wayne has talked about it a few times, and allegedly he even drinks it in an interview.
And in "Make It Rain Fat Joe feat. Lil Wayne," Fat Joe Talks about it in a line in his verse.
"Couple Bricks Stacked up on that triple beam, my dirty bro sippin that PROMETHAZEEN" (Joe talkin bout Weezy drinkin it)
SO WHAT IS IT?
Purple drank is a slang term for a concoction which includes a prescription-strength cough syrup used in a manner inconsistent with its labeling, as a recreational drug.
Learn More http://en.wikipedia.org/wiki/Purple_drank
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